Ulcerative Colitis
Ulcerative colitis (IBD) affects the colon and rectum. It causes persistent colon and rectum ulcers, stomach discomfort, diarrhoea, and other symptoms.Ulcerative colitis is considered to be caused by an aberrant immune system response that inflames the colon and rectum.
These may cause ulcerative colitis:
Genetics: Ulcerative colitis runs in families, and specific genetic variants may increase the risk.
Environmental factors: A high-fat diet, stress, and germs or viruses might increase symptoms in genetically predisposed ulcerative colitis patients.
Abnormal immune response: It is thought that an abnormal immune response in the colon and rectum may cause inflammation and ulceration in people with ulcerative colitis.
Gut microbiome: Changes in the billions of gut microbes may cause ulcerative colitis.
Smoking: Smoking cigarettes increases the risk of ulcerative colitis and worsens its symptoms.
Age: Ulcerative colitis is most common among 15–30-year-olds.
Ulcerative colitis may cause:
Diarrhoea: Stools may contain blood, pus, or mucus.
Abdominal cramping and pain: Usually on the lower left side.
Rectal pain: You may feel like you need to go to the bathroom all the time.
Weight loss: diarrhoea and loss of appetite can cause this.
Fatigue: Anaemia or inflammation may cause this.
Fever: A severe flare-up may cause this.
Dehydration: diarrhoea and decreased water absorption can cause this.
Joint pain: It affects the joints.
Rashes and sores: Ulcerative colitis causes skin issues.
Eye problems: Ulcerative colitis can cause uveitis in rare cases.
Some ulcerative colitis patients have repeated flare-ups with severe symptoms, while others go into remission for lengthy periods.
Ulcerative colitis complications include:
Severe bleeding: Chronic colon inflammation and ulceration can cause severe bleeding, anaemia, and fatigue.
Perforation: Severe colon inflammation and ulceration may weaken the gut walls, causing a life-threatening hole (perforation).
Toxic megacolon: an uncommon ulcerative colitis consequence in which the colon becomes extremely inflamed and swollen, possibly causing death.
Increased risk of colon cancer: Ulcerative colitis increases the risk of colon cancer, particularly in long-term sufferers.
Malnutrition: Chronic diarrhoea, poor food absorption, and appetite loss may cause malnutrition and weight loss.
Osteoporosis: Ulcerative colitis may increase the risk of this bone-weakening disease.
Joint pain and inflammation: Ulcerative colitis can cause joint pain.
Uveitis: Ulcerative colitis can occasionally cause eye inflammation.